Determinants of bleeding phenotype in adult patients with moderate or severe von Willebrand disease

M. de Wee, Eva; Sanders, Yvonne; P. Mauser‐Bunschoten, Eveline; G. van der Bom, Johanna; Degenaar-Dujardin, M.; Eikenboom, Jeroen; de Goede-Bolder, Arja; A. P. Laros‐van Gorkom, Britta; Meijer, Karina; Hamulyák, Karly; R. Nijziel, Marten; Fijnvandraat, Karin; W.G. Leebeek, Frank; the WiN study group, for

doi:10.1160/th12-04-0244

Public

Determinants of bleeding phenotype in adult patients with moderate or severe von Willebrand disease

Published in Thrombosis and Haemostasis • Jan 1, 2012

Authors:

Eva M. de Wee

Yvonne Sanders

Eveline P. Mauser‐Bunschoten

Abstract

We performed a nation-wide cross-sectional study to evaluate determinants of bleeding symptoms in a large unselected cohort of adults with von Willebrand disease (VWD). VWD patients were included (n=664), based on lowest historically measured VWF:Ag and VWF:Act levels ≤30 U/dl. Menorrhagia (85%), cu...

Subject

Von Willebrand disease

Medicine

Von Willebrand factor

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