Evidence for Functional Relevance of an Enhanced Expression of the Na <sup>+</sup> -Ca <sup>2+</sup> Exchanger in Failing Human Myocardium

Flesch, Markus; H. G. Schwinger, Robert; Schiffer, Frank; Frank, Konrad; Su ̈dkamp, Michael; Kuhn‐Régnier, Ferdinand; J. Arnold, Georg; Bo ̈hm, Michael

doi:10.1161/01.cir.94.5.992

Public

Evidence for Functional Relevance of an Enhanced Expression of the Na + -Ca 2+ Exchanger in Failing Human Myocardium

Published in Circulation • Sep 1, 1996

Authors:

Markus Flesch

Robert H. G. Schwinger

Frank Schiffer

Abstract

BACKGROUND: The present study aimed at investigating the expression of the Na(+)-Ca2+ exchanger and its functional role in human failing myocardium. METHODS AND RESULTS: Na(+)-Ca2+ exchanger mRNA and protein levels were examined in nonfailing (NF, n = 8) and failing human myocardium (New York Heart ...

Subject

Inotrope

Internal medicine

Medicine

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