Comparative Immunogenicity in Rhesus Monkeys of DNA Plasmid, Recombinant Vaccinia Virus, and Replication-Defective Adenovirus Vectors Expressing a Human Immunodeficiency Virus Type 1 <i>gag</i> Gene

R. Casimiro, Danilo; Chen, Ling; Fu, Tong‐Ming; K. Evans, Robert; J. Caulfield, Michael; Davies, Mary-Ellen; Tang, Aimin; Chen, Minchun; Huang, Lingyi; Harris, Virginia; C. Freed, Daniel; Wilson, Keith; Dubey, Sheri; Zhu, De‐Min; K. Nawrocki, Denise; Mach, Henryk; D. Troutman, Robert; A. Isopi, Lynne; M. Williams, Donna; M. Hurni, William; Xu, Zheng; G. Smith, Jeffrey; Wang, Su; Liu, Xu; Guan, Liming; Long, Romnie; L. Trigona, Wendy; J. Heidecker, Gwendolyn; C. Perry, Helen; Persaud, Natasha; J. Toner, Timothy; Su, Qin; Liang, Xiaoping; Youil, Rima; Chastain, Michael; J. Bett, Andrew; B. Volkin, David; A. Emini, Emilio; W. Shiver, John

doi:10.1128/jvi.77.11.6305-6313.2003

Public

Comparative Immunogenicity in Rhesus Monkeys of DNA Plasmid, Recombinant Vaccinia Virus, and Replication-Defective Adenovirus Vectors Expressing a Human Immunodeficiency Virus Type 1 gag Gene

Published in Journal of Virology • May 12, 2003

Authors:

Danilo R. Casimiro

Ling Chen

Tong‐Ming Fu

Abstract

Cellular immune responses, particularly those associated with CD3(+) CD8(+) cytotoxic T lymphocytes (CTL), play a primary role in controlling viral infection, including persistent infection with human immunodeficiency virus type 1 (HIV-1). Accordingly, recent HIV-1 vaccine research efforts have focu...

Subject

Virology

Biology

Immunogenicity

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