Trial of short-course antimicrobial therapy for intraabdominal infection.

RG, Sawyer; JA, Claridge; AB, Nathens; OD, Rotstein; TM, Duane; HL, Evans; CH, Cook; PJ, O'Neill; JE, Mazuski; R, Askari; MA, Wilson; LM, Napolitano; N, Namias; PR, Miller; EP, Dellinger; CM, Watson; R, Coimbra; DL, Dent; SF, Lowry; CS, Cocanour; MA, West; KL, Banton; WG, Cheadle; PA, Lipsett; CA, Guidry; K, Popovsky

doi:10.1056/nejmoa1411162

Public

Trial of short-course antimicrobial therapy for intraabdominal infection.

Shared by NobleBlocks on May 1, 2015 • 12:00 AM UTC

Authors:

Sawyer RG

Claridge JA

Nathens AB

Abstract

Background The successful treatment of intraabdominal infection requires a combination of anatomical source control and antibiotics. The appropriate duration of antimicrobial therapy remains unclear.Methods We randomly assigned 518 patients with complicated intraabdominal infection and adequate sour...

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