Simultaneous production of IL-2, IL-4, and IFN-gamma by activated human CD4+ and CD8+ T cell clones.

Paliard, Xavier; de Waal Malefijt, R; Yssel, Hans; Blanchard, Dominique; Chrétien, Isabelle; S Abrams, J; de Vries, JE; Spits, Hergen

doi:10.4049/jimmunol.141.3.849

Public

Simultaneous production of IL-2, IL-4, and IFN-gamma by activated human CD4+ and CD8+ T cell clones.

Published in The Journal of Immunology • Aug 1, 1988

Authors:

Xavier Paliard

R de Waal Malefijt

Hans Yssel

Abstract

In the present study, we have investigated the ability of human T cells to secrete IL-2, IL-4, and IFN-gamma. IL-4 and IFN-gamma were quantified with enzymatic immunoassays and IL-2 with a biologic assay by using the murine IL-2-dependent cell line CTLL-2. PBL, stimulated with Con A or with a combin...

Subject

Lymphokine

Secretion

Stimulation

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