Mutations of the <b>
                     <i>Epidermal Growth Factor Receptor</i>
                  </b> Gene in Lung Cancer

Kosaka, Takayuki; Yatabe, Yasushi; Endoh, Hideki; Kuwano, Hiroyuki; Takahashi, Takashi; Mitsudomi, Tetsuya

doi:10.1158/0008-5472.can-04-2818

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Mutations of the Epidermal Growth Factor Receptor Gene in Lung Cancer

Shared by NobleBlocks on Dec 15, 2004 • 12:00 AM UTC

Authors:

Takayuki Kosaka

Yasushi Yatabe

Hideki Endoh

Abstract

Abstract Recently it has been reported that mutations in the tyrosine kinase domain of the epidermal growth factor receptor(EGFR) gene occur in a subset of patients with lung cancer showing a dramatic response to EGFR tyrosine kinase inhibitors. To gain further insights in the role of EGFR in lung c...

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