Assessment of an Optimized Mycobacterial Interspersed Repetitive- Unit-Variable-Number Tandem-Repeat Typing System Combined with Spoligotyping for Population-Based Molecular Epidemiology Studies of Tuberculosis

Cardoso Oelemann, Mara; Diel, Roland; Vatin, Vincent; Haas, Walter; Rüsch–Gerdes, Sabine; Locht, Camille; Niemann, Stefan; Supply, Philip

doi:10.1128/jcm.01393-06

Public

Assessment of an Optimized Mycobacterial Interspersed Repetitive- Unit-Variable-Number Tandem-Repeat Typing System Combined with Spoligotyping for Population-Based Molecular Epidemiology Studies of Tuberculosis

Published in Journal of Clinical Microbiology • Dec 28, 2006

Authors:

Mara Cardoso Oelemann

Roland Diel

Vincent Vatin

Abstract

An optimized set of 24 mycobacterial interspersed repetitive-unit-variable-number tandem-repeat (MIRU-VNTR) loci, including a discriminatory subset of 15 loci, has recently been defined for the typing of Mycobacterium tuberculosis. Here, we evaluated the performances of this MIRU-VNTR typing system ...

Subject

Typing

Genotyping

Variable number tandem repeat

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