Differential activation profiles of Crimean-Congo hemorrhagic fever virus- and Dugbe virus-infected antigen-presenting cells.

CN, Peyrefitte; M, Perret; S, Garcia; R, Rodrigues; A, Bagnaud; S, Lacote; JM, Crance; G, Vernet; D, Garin; M, Bouloy; G, Paranhos-Baccalà

doi:10.1099/vir.0.015701-0

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Differential activation profiles of Crimean-Congo hemorrhagic fever virus- and Dugbe virus-infected antigen-presenting cells.

Shared by NobleBlocks on Oct 7, 2009 • 12:00 AM UTC

Authors:

Peyrefitte CN

Perret M

Garcia S

Abstract

Crimean-Congo hemorrhagic fever virus (CCHFV) is a highly pathogenic, tick-borne member of the family Bunyaviridae and the genus Nairovirus. To better elucidate the pathogenesis of CCHFV, we analysed the host innate immune response induced in antigen-presenting cells (APCs) infected in vitro by CCHF...

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