Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study

Conter, Valentino; R. Bartram, Claus; Grazia Valsecchi, Maria; Schrauder, André; Panzer‐Grümayer, Renate; Möricke, Anja; Aricò, Maurizio; Zimmermann, Martin; Mann, Georg; Rossi, Giulio; Stanulla, Martin; Locatelli, Franco; Basso, Giuseppe; Niggli, Felix; Barisone, Elena; Henze, Günter; Ludwig, Wolfgang; A. Haas, Oskar; Cazzaniga, Giovanni; Koehler, Rolf; Silvestri, Daniela; Bradtke, Jutta; Parasole, Rosanna; Beier, Rita; J. M. van Dongen, Jacques; Biondi, Andrea; Schrappe, Martin

doi:10.1182/blood-2009-10-248146

Public

Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study

Published in Blood • Feb 12, 2010

Authors:

Valentino Conter

Claus R. Bartram

Maria Grazia Valsecchi

Abstract

The Associazione Italiana di Ematologia Oncologia Pediatrica and the Berlin-Frankfurt-Münster Acute Lymphoblastic Leukemia (AIEOP-BFM ALL 2000) study has for the first time introduced standardized quantitative assessment of minimal residual disease (MRD) based on immunoglobulin and T-cell receptor g...

Subject

Minimal residual disease

Medicine

Internal medicine

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