Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

Mahajan, Anubha; Jin Go, Min; Zhang, Weihua; E. Below, Jennifer; J. Gaulton, Kyle; Ferreira, Teresa; Horikoshi, Momoko; D. Johnson, Andrew; C. Y. Ng, Maggie; Prokopenko, Inga; Saleheen, Danish; Wang, Xu; Zeggini, Eleftheria; R. Abecasis, Gonçalo; S. Adair, Linda; Almgren, Peter; Atalay, Mustafa; Aung, Tin; Baldassarre, Damiano; Balkau, Beverley; Bao, Yuqian; Barnett, Anthony; Barroso, Inês; Basit, Abdul; Been, Latonya; Beilby, John; I. Bell, Graeme; Benediktsson, Rafn; N. Bergman, Richard; O. Boehm, Bernhard; Boerwinkle, Eric; L. Bonnycastle, Lori; P. Burtt, Noël; Cai, Qiuyin; Campbell, Harry; Carey, Jason; Cauchi, Stéphane; J. Caulfield, Mark; C.N. Chan, Juliana; Chang, Li-Ching; Chang, Tien‐Jyun; Chang, Yi‐Cheng; Charpentier, G.; Chen, Chien-Hsiun; Chen, Han; Chen, Yuan-Tsong; Chia, Kee‐Seng; Chidambaram, Manickam; S. Chines, Peter; H. Cho, Nam; Min Cho, Young; Chuang, Lee‐Ming; S. Collins, Francis; C. Cornelis, Marilyn; Couper, David; Crenshaw, Andrew; M. van Dam, Rob; Danesh, John; Das, Debashish; dé Fairé, Ulf; Dedoussis, George; Deloukas, Panos; S. Dimas, Antigone; Dina, Christian; S. F. Doney, Alex; Donnelly, Peter; Dorkhan, Mozhgan; M. van Duijn, Cornelia; Dupuis, Josée; Edkins, Sarah; Elliott, Paul; Emilsson, Valur; Erbel, Raimund; G. Eriksson, Johan; Escobedo, Jorge; Esko, Tõnu; Eury, Elodie; C. Florez, José; Fontanillas, Pierre; G. Forouhi, Nita; Forsén, Tom; S. Fox, Caroline; M. Fraser, Ross; M. Frayling, Timothy; Froguel, Philippe; Frossard, Philippe; Gao, Yu‐Tang; Gertow, Karl; Gieger, Christian; Gigante, Bruna; Grallert, Harald; Grant, George; Groop, Leif; J. Groves, Christopher; Grundberg, Elin; Guiducci, Candace; Hamsten, Anders; Han, Bok‐Ghee; Hara, Kazuo; Hassanali, Neelam; T. Hattersley, Andrew; Hayward, Caroline; K. Hedman, Åsa; Herder, Christian; Hofman, Albert; L. Holmen, Oddgeir; Hovingh, Kees; B. Hreiðarsson, Ástráður; Hu, Cheng; B. Hu, Frank; Hui, Jennie; E. Humphries, Steve; Hunt, Sarah; J. Hunter, David; Hveem, Kristian; Zafar Iqbal Hydrie, Muhammad; Ikegami, Hiroshi; Illig, Thomas; Ingelsson, Erik; Islam, Muhammed; Isomaa, Bo; Jackson, Anne; Jafar, Tazeen; James, Alan; Jia, Weiping; Jöckel, Karl‐Heinz; Jonsson, Anna; B. M. Jowett, Jeremy; Kadowaki, Takashi; Min Kang, Hyun; Kanoni, Stavroula; Hong Linda Kao, Wen; Kathiresan, Sekar; Kato, Norihiro; Katulanda, Prasad; Keinänen‐Kiukaanniemi, Sirkka; M Kelly, Ann; Khan, Hassan; Khaw, Kay‐Tee; Chuen Khor, Chiea; Kim, Hyung-Lae; Soo Kim, Sang; Jin Kim, Young; Kinnunen, Leena; Klopp, Norman; Kong, Augustine; Korpi-Hyövälti, Eeva; Kowlessur, Sudhir; Kraft, Peter; Kravić, Jasmina; M. Kristensen, Malene; Krithika, S.; Kumar, Ashish; Kumate, J; Kuusisto, Johanna; Heon Kwak, Soo; Laakso, Markku; Lagou, Vasiliki; A. Lakka, Timo; Langenberg, Claudia; Langford, Cordelia; Lawrence, Robert; Leander, Karin; Lee, Jen-Mai; Lee, Sang; Li, Man; Li, Man; Li, Yun; Liang, Junbin; Liju, Samuel; Lim, Wei‐Yen; Lind, Lars; M. Lindgren, Cecilia; Lindholm, Eero; Liu, Ching‐Ti; Liu, Jianjun; Lobbens, Stéphane; Long, Jirong; J. F. Loos, Ruth; Lu, Wei; Luan, Jian’an; Lyssenko, Valeriya; C.W., Ronald; Maeda, Shiro; Mägi, Reedik; Männistö, Satu; R Matthews, David; B. Meigs, James; Melander, Olle; Metspalu, Andres; Meyer, Julia; Mirza, Ghazala; Mihailov, Evelin; Moebus, Susanne; Mohan, Viswanathan; L. Mohlke, Karen; D. Morris, Andrew; W Mühleisen, Thomas; Müller‐Nurasyid, Martina; Musk, Bill; Nakamura, Jiro; Nakashima, Eitaro; Navarro, Pau; Ng, Peng-Keat; C. Nica, Alexandra; M. Nilsson, Peter; Njølstad, Inger; M. Nöthen, Markus; Ohnaka, Keizo; Hee Ong, Twee; R. Owen, Katharine; N A Palmer, Colin; S. Pankow, James; Soo Park, Kyong; Parkin, Melissa; Pechlivanis, Sonali; L. Pedersen, Nancy; Peltonen, Leena; R. B. Perry, John; Peters, Annette; Pinidiyapathirage, Janani; Platou, Carl; Potter, Simon; F. Price, Jackie; Qi, Lu; Radha, Venkatesan; S. Rallidis, Lοukianos; Rasheed, Asif; Rathmann, Wolfgang; Rauramaa, Rainer; Raychaudhuri, Soumya; W. Rayner, Nigel; D. Rees, Simon; Rehnberg, Emil; Ripatti, Samuli; Robertson, Neil; Roden, Michael; J. Rossin, Elizabeth; Rudan, Igor; Rybin, Denis; Saaristo, Timo; Salomaa, Veikko; Saltevo, Juha; Samuel, Maria; K. Sanghera, Dharambir; Saramies, Jouko; Scott, James; J. Scott, Laura; A. Scott, Robert; V. Segrè, Ayellet; Sehmi, Joban; Sennblad, Bengt; Shah, Nabi; Shah, Sonia; Samad Shera, A.; Ou Shu, Xiao; R. Shuldiner, Alan; Sigurðsson, Gunnar; J.G. Sijbrands, Eric; Silveira, Angela; Sim, Xueling; Sivapalaratnam, Suthesh; S. Small, Kerrin; Yee So, Wing; Stančáková, Alena; Stefánsson, Kāri; Steinbach, Gerald; Steinthórsdóttir, Valgerður; Stirrups, Kathleen; J. Strawbridge, Rona; M. Stringham, Heather; Sun, Qi; Suo, Chen; Syvänen, Ann‐Christine; Takayanagi, Ryoichi; Takeuchi, Fumihiko; Ting Tay, Wan; M. Teslovich, Tanya; Thorand, Barbara; Þorleifsson, Guðmar; Þorsteinsdóttir, Unnur; Tikkanen, Emmi; Trakalo, Joseph; Tremoli, Elena; D. Trip, Mieke; Jen Tsai, Fuu; Tuomi, Tiinamaija; Tuomilehto, Jaakko; G. Uitterlinden, André; Valladares‐Salgado, Adán; Vedantam, Sailaja; Veglia, Fabrizio; F. Voight, Benjamin; Wang, Congrong; J. Wareham, Nicholas; Wennauer, Roman; R. Wickremasinghe, Ananda; Wilsgaard, Tom; F. Wilson, James; Wiltshire, Steven; Winckler, Wendy; Yin Wong, Tien; R. Wood, Andrew; Wu, Jer‐Yuarn; Wu, Ying; Yamamoto, Ken; Yamauchi, Toshimasa; Yang, Ming‐Yu; Yengo, Loïc; Yokota, Mitsuhiro; Young, Robin; Zabaneh, Delilah; Zhang, Fan; Zhang, Rong; Zheng, Wei; Zimmet, Paul; Altshuler, David; W. Bowden, Donald; Shin Cho, Yoon; J. Cox, Nancy; Cruz, Miguel; L. Hanis, Craig; S. Kooner, Jaspal; Lee, Jong‐Young; Seielstad, Mark; Ying Teo, Yik; Boehnke, Michael; J. Parra, Esteban; C. Chambers, John; Shyong Tai, E; I. McCarthy, Mark; P. Morris, Andrew

doi:10.1038/ng.2897

Public

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

Published in Nature Genetics • Feb 9, 2014

Authors:

Anubha Mahajan

Min Jin Go

Weihua Zhang

Abstract

Andrew Morris, Mark McCarthy, Michael Boehnke and colleagues report a meta-analysis of genome-wide association studies for type 2 diabetes, including 26,488 cases and 83,964 controls from populations of European, east Asian, south Asian and Mexican and Mexican American ancestry. They identify seven ...

Subject

Genome-wide association study

Biology

Genetic architecture

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!