A 2‐oxoglutarate‐dependent dioxygenase from Ruta graveolens L. exhibits p‐ coumaroyl CoA 2′‐hydroxylase activity (C2′H): a missing step in the synthesis of umbelliferone in plants

Vialart, Guilhem; Hehn, Alain; Olry, Alexandre; Ito, Kyoko; Krieger, Célia; Larbat, Romain; Paris, Cédric; Shimizu, Bun‐ichi; Sugimoto, Yukihiro; Mizutani, Masaharu; Bourgaud, Frédéric

doi:10.1111/j.1365-313x.2011.04879.x

Public

A 2‐oxoglutarate‐dependent dioxygenase from Ruta graveolens L. exhibits p‐ coumaroyl CoA 2′‐hydroxylase activity (C2′H): a missing step in the synthesis of umbelliferone in plants

Published in The Plant Journal • Dec 13, 2011

Authors:

Guilhem Vialart

Alain Hehn

Alexandre Olry

Abstract

Coumarins are important compounds that contribute to the adaptation of plants to biotic or abiotic stresses. Among coumarins, umbelliferone occupies a pivotal position in the plant phenylpropanoid network. Previous studies indicated that umbelliferone is derived from the ortho-hydroxylation of p-cou...

Subject

Umbelliferone

Scopoletin

Furanocoumarin

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