Distribution pattern of the Ki67 labelling index in breast cancer and its implications for choosing cut-off values

Cserni, Gábor; Vörös, András; Liepniece‐Karele, Inta; Bianchi, Simonetta; Vezzosi, Vania; Grabau, Dorthe; Sapino, Anna; Castellano, Isabella; Regitnig, Peter; Pia Foschini, Maria; Zolota, Vassiliki; Varga, Zsuzsanna; Figueiredo, Paulo; Decker, Thomas; M. Focke, Cornelia; Kulka, Janina; Kaya, Handan; Reiner‐Concin, Angelika; Amendoeira, Isabel; Callagy, Grace; Caffrey, Emer; Wesseling, Jelle; Wells, Clive

doi:10.1016/j.breast.2014.02.003

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Distribution pattern of the Ki67 labelling index in breast cancer and its implications for choosing cut-off values

Published in The Breast • Mar 9, 2014

Authors:

Gábor Cserni

András Vörös

Inta Liepniece‐Karele

Abstract

The Ki67 labelling index (LI - proportion of staining cells) is widely used to reflect proliferation in breast carcinomas. Several cut-off values have been suggested to distinguish between tumours with low and high proliferative activity. The aim of the current study was to evaluate the distribution...

Subject

Medicine

Breast cancer

Mitotic index

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