Genetic polymorphism of alcohol dehydrogenase in europeans: The ADH2*2 allele decreases the risk for alcoholism and is associated with ADH3*1

Borràs, Emma; Coutelle, C.; Rosell, Albert; Fernández-Muixí, Fina; Broch, Montserrat; Crosas, Bernat; Hjelmqvist, Lars; Lorenzo, Alfons; Gutiérrez, Cristina; Santos, Mauro; Szczepanek, Małgorzata; Heilig, Markus; Quattrocchi, Pierrette; Farrés, Jaume; Vidal, Francesc; Richart, Cristóbal; Mach, Tomasz; Bogdał, Józef; Jörnvall, Hans; K. Seitz, Helmut; Couzigou, Patrice; Parés, Xavier

doi:10.1053/he.2000.5978

Public

Genetic polymorphism of alcohol dehydrogenase in europeans: The ADH22 allele decreases the risk for alcoholism and is associated with ADH31

Published in Hepatology • Apr 1, 2000

Authors:

Emma Borràs

C. Coutelle

Albert Rosell

Abstract

Polymorphism at the ADH2 and ADH3 loci of alcohol dehydrogenase (ADH) has been shown to have an effect on the predisposition to alcoholism in Asian individuals. However, the results are not conclusive for white individuals. We have analyzed the ADH genotype of 876 white individuals from Spain (n = 2...

Subject

Allele

Alcohol dehydrogenase

Genetics

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