Evidence Based Selection of Housekeeping Genes

J.M. de Jonge, Hendrik; S.N. Fehrmann, Rudolf; S.J.M. de Bont, Eveline; M.W. Hofstra, Robert; Gerbens, Frans; A. Kamps, Willem; G.E. de Vries, Elisabeth; G.J. van der Zee, Ate; J. te Meerman, Gerard; ter Elst, Arja

doi:10.1371/journal.pone.0000898

Public

Evidence Based Selection of Housekeeping Genes

Published in PLoS ONE • Sep 18, 2007

Authors:

Hendrik J.M. de Jonge

Rudolf S.N. Fehrmann

Eveline S.J.M. de Bont

Abstract

For accurate and reliable gene expression analysis, normalization of gene expression data against housekeeping genes (reference or internal control genes) is required. It is known that commonly used housekeeping genes (e.g. ACTB, GAPDH, HPRT1, and B2M) vary considerably under different experimental ...

Subject

Housekeeping gene

Gene

Biology

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