Late Side Effects of Short-Course Preoperative Radiotherapy Combined With Total Mesorectal Excision for Rectal Cancer: Increased Bowel Dysfunction in Irradiated Patients—A Dutch Colorectal Cancer Group Study

Peeters, K.C.M.J.; van de Velde, C.J.H.; Leer, J.W.H.; Martijn, H.; Junggeburt, J.M.C.; Klein Kranenbarg, E.; Steup, W.H.; Wiggers, T.; Rutten, H.J.; Marijnen, C.A.M.

doi:10.1200/jco.2005.14.779

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Late Side Effects of Short-Course Preoperative Radiotherapy Combined With Total Mesorectal Excision for Rectal Cancer: Increased Bowel Dysfunction in Irradiated Patients—A Dutch Colorectal Cancer Group Study

Shared by NobleBlocks on Sep 1, 2005 • 12:00 AM UTC

Authors:

K.C.M.J. Peeters

C.J.H. van de Velde

J.W.H. Leer

Abstract

Purpose Preoperative short-term radiotherapy improves local control in patients treated with total mesorectal excision (TME). This study was performed to assess the presence and magnitude of long-term side effects of preoperative 5 × 5 Gy radiotherapy and TME. Also, hospital treatment was recorded f...

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