Initial Safety Report of NSABP C-08: A Randomized Phase III Study of Modified FOLFOX6 With or Without Bevacizumab for the Adjuvant Treatment of Patients With Stage II or III Colon Cancer

J. Allegra, Carmen; Yothers, Greg; J. O’Connell, Michael; Sharif, Saima; H. Colangelo, Linda; Lopa, Samia; J. Petrelli, Nicholas; M. Goldberg, Richard; N. Atkins, James; E. Seay, Thomas; Fehrenbacher, Louis; O’Reilly, Séamus; Chu, Luis; A. Azar, Catherine; Wolmark, Norman

doi:10.1200/jco.2009.21.9220

Public

Initial Safety Report of NSABP C-08: A Randomized Phase III Study of Modified FOLFOX6 With or Without Bevacizumab for the Adjuvant Treatment of Patients With Stage II or III Colon Cancer

Published in Journal of Clinical Oncology • May 5, 2009

Authors:

Carmen J. Allegra

Greg Yothers

Michael J. O’Connell

Abstract

PURPOSE: The National Surgical Adjuvant Breast and Bowel Project C-08 trial was designed to investigate the safety and effectiveness of adding bevacizumab to modified infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX) 6 regimen for the adjuvant treatment of patients with stage II or III c...

Subject

Medicine

Bevacizumab

Oxaliplatin

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