Personalized Oncology Through Integrative High-Throughput Sequencing: A Pilot Study

Roychowdhury, Sameek; K. Iyer, Matthew; R. Robinson, Dan; J. Lonigro, Robert; Wu, Yi-Mi; Cao, Xuhong; Kalyana‐Sundaram, Shanker; Sam, Lee; Alejandro Balbin, O.; J. Quist, Michael; R. Barrette, Terrence; N. Everett, Jessica; Siddiqui, Javed; P. Kunju, Lakshmi; M. Navone, Nora; C. Araujo, John; Troncoso, Patricia; J. Logothetis, Christopher; W. Innis, Jeffrey; C. Smith, David; D. Lao, Christopher; Y. H. Kim, Scott; Scott Roberts, J.; B. Gruber, Stephen; J. Pienta, Kenneth; Talpaz, Moshe; M. Chinnaiyan, Arul

doi:10.1126/scitranslmed.3003161

Public

Personalized Oncology Through Integrative High-Throughput Sequencing: A Pilot Study

Published in Science Translational Medicine • Nov 30, 2011

Authors:

Sameek Roychowdhury

Matthew K. Iyer

Dan R. Robinson

Abstract

Individual cancers harbor a set of genetic aberrations that can be informative for identifying rational therapies currently available or in clinical trials. We implemented a pilot study to explore the practical challenges of applying high-throughput sequencing in clinical oncology. We enrolled patie...

Subject

Neuroblastoma RAS viral oncogene homolog

KRAS

HRAS

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!