Sunitinib versus Interferon Alfa in Metastatic Renal-Cell Carcinoma

J. Motzer, Robert; E. Hutson, Thomas; Tomczak, Piotr; Dror Michaelson, M.; M. Bukowski, Ronald; Rixe, Olivier; Oudard, Stéphane; Négrier, Sylvie; Szczylik, Cezary; T. Kim, Sindy; Chen, Isan; Bycott, Paul; M. Baum, Charles; A. Figlin, Robert

doi:10.1056/nejmoa065044

Public

Sunitinib versus Interferon Alfa in Metastatic Renal-Cell Carcinoma

Published in New England Journal of Medicine • Jan 10, 2007

Authors:

Robert J. Motzer

Thomas E. Hutson

Piotr Tomczak

Abstract

BACKGROUND: Since sunitinib malate has shown activity in two uncontrolled studies in patients with metastatic renal-cell carcinoma, a comparison of the drug with interferon alfa in a phase 3 trial is warranted. METHODS: We enrolled 750 patients with previously untreated, metastatic renal-cell carcin...

Subject

Medicine

Sunitinib

Renal cell carcinoma

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