Efficient genome engineering in human pluripotent stem cells using Cas9 from <i>Neisseria meningitidis</i>

Hou, Zhonggang; Zhang, Yan; E. Propson, Nicholas; E. Howden, Sara; Chu, Li‐Fang; J. Sontheimer, Erik; A. Thomson, James

doi:10.1073/pnas.1313587110

Public

Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis

Published in Proceedings of the National Academy of Sciences • Aug 12, 2013

Authors:

Zhonggang Hou

Yan Zhang

Nicholas E. Propson

Abstract

Genome engineering in human pluripotent stem cells (hPSCs) holds great promise for biomedical research and regenerative medicine. Recently, an RNA-guided, DNA-cleaving interference pathway from bacteria [the type II clustered, regularly interspaced, short palindromic repeats (CRISPR)-CRISPR-associat...

Subject

CRISPR

Cas9

Genome editing

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!