A Randomized Trial of Glutamine and Antioxidants in Critically Ill Patients

K. Heyland, Daren; Muscedere, John; E. Wischmeyer, Paul; Cook, Deborah; Jones, Gwynne; Albert, Martin; Elke, Gunnar; M. Berger, Mette; G. Day, Andrew

doi:10.1056/nejmoa1212722

Public

A Randomized Trial of Glutamine and Antioxidants in Critically Ill Patients

Published in New England Journal of Medicine • Apr 17, 2013

Authors:

Daren K. Heyland

John Muscedere

Paul E. Wischmeyer

Abstract

BACKGROUND: Critically ill patients have considerable oxidative stress. Glutamine and antioxidant supplementation may offer therapeutic benefit, although current data are conflicting. METHODS: In this blinded 2-by-2 factorial trial, we randomly assigned 1223 critically ill adults in 40 intensive car...

Subject

Medicine

Glutamine

Odds ratio

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