Humoral Responses to<i>Plasmodium falciparum</i>Blood-Stage Antigens and Association with Incidence of Clinical Malaria in Children Living in an Area of Seasonal Malaria Transmission in Burkina Faso, West Africa

Nébié, Issa; Diarra, Amidou; Ouédraogo, Alphonse; Soulama, Issiaka; C. Bougouma, Edith; B. Tiono, Alfred; T. Konaté, Amadou; Chilengi, Roma; Theisen, Michael; Dodoo, Daniel; Remarque, Ed; Bosomprah, Samuel; Milligan, Paul; B. Sirima, Sodiomon

doi:10.1128/iai.01147-07

Public

Humoral Responses toPlasmodium falciparumBlood-Stage Antigens and Association with Incidence of Clinical Malaria in Children Living in an Area of Seasonal Malaria Transmission in Burkina Faso, West Africa

Published in Infection and Immunity • Dec 11, 2007

Authors:

Issa Nébié

Amidou Diarra

Alphonse Ouédraogo

Abstract

There is longstanding evidence that immunoglobulin G (IgG) has a role in protection against clinical malaria, and human antibodies of the cytophilic subclasses are thought to be particularly critical in this respect. In this cohort study, 286 Burkinabè children 6 months to 15 years old were kept und...

Subject

Malaria

Malaria vaccine

Parasitemia

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