Vascular imprints of neuronal activity: Relationships between the dynamics of cortical blood flow, oxygenation, and volume changes following sensory stimulation

Malonek, Dov; Dirnagl, Ulrich; Lindauer, Ute; Yamada, Katsuya; Kanno, Iwao; Grinvald, Amiram

doi:10.1073/pnas.94.26.14826

Public

Vascular imprints of neuronal activity: Relationships between the dynamics of cortical blood flow, oxygenation, and volume changes following sensory stimulation

Published in Proceedings of the National Academy of Sciences • Dec 23, 1997

Authors:

Dov Malonek

Ulrich Dirnagl

Ute Lindauer

Abstract

Modern functional neuroimaging methods, such as positron-emission tomography (PET), optical imaging of intrinsic signals, and functional MRI (fMRI) utilize activity-dependent hemodynamic changes to obtain indirect maps of the evoked electrical activity in the brain. Whereas PET and flow-sensitive MR...

Subject

Cerebral blood flow

Blood flow

Deoxygenated Hemoglobin

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