1,25-dihydroxyvitamin D3 production and vitamin D3 receptor expression are developmentally regulated during differentiation of human monocytes into macrophages

Kreutz, Marina; Andreesen, Reinhard; W. Krause, Stefan; Szabó, András; Ritz, Eberhard; Reichel, Helmut

doi:10.1182/blood.v82.4.1300.1300

Public

1,25-dihydroxyvitamin D3 production and vitamin D3 receptor expression are developmentally regulated during differentiation of human monocytes into macrophages

Published in Blood • Aug 15, 1993

Authors:

Marina Kreutz

Reinhard Andreesen

Stefan W. Krause

Abstract

It has been well established that human mononuclear phagocytes have the capacity to produce 1,25-dihydroxy-vitamin D3 [1,25(OH)3D3] and express the vitamin D receptor (VDR). However, 1 alpha-hydroxylase activity and VDR receptor expression during differentiation of monocytes (MO) into mature macroph...

Subject

Calcitriol receptor

Internal medicine

Endocrinology

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