Molecular basis and mechanisms of drug resistance in Mycobacterium tuberculosis: classical and new drugs

E. A. da Silva, Pedro; Carlos Palomino, Juan

doi:10.1093/jac/dkr173

Public

Molecular basis and mechanisms of drug resistance in Mycobacterium tuberculosis: classical and new drugs

Published in Journal of Antimicrobial Chemotherapy • May 9, 2011

Authors:

Pedro E. A. da Silva

Juan Carlos Palomino

Abstract

Tuberculosis (TB) remains one of the leading public health problems worldwide. Declared as a global emergency in 1993 by the WHO, its control is hampered by the emergence of multidrug resistance (MDR), defined as resistance to at least rifampicin and isoniazid, two key drugs in the treatment of the ...

Subject

Tuberculosis

Mycobacterium tuberculosis

Rifampicin

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