Blood-derived dermal langerin+ dendritic cells survey the skin in the steady state

Ginhoux, Florent; P. Collin, Matthew; Bogunovic, Milena; Abel, Michal; Leboeuf, Marylene; Helft, Julie; Ochando, Jordi; Kissenpfennig, Adrien; Malissen, Bernard; Grisotto, Marcos; Snoeck, Hans; Randolph, Gwendalyn; Merad, Miriam

doi:10.1084/jem.20071733

Public

Blood-derived dermal langerin+ dendritic cells survey the skin in the steady state

Shared by NobleBlocks on Dec 17, 2007 • 12:00 AM UTC

Authors:

Florent Ginhoux

Matthew P. Collin

Milena Bogunovic

Abstract

Langerin is a C-type lectin receptor that recognizes glycosylated patterns on pathogens. Langerin is used to identify human and mouse epidermal Langerhans cells (LCs), as well as migratory LCs in the dermis and the skin draining lymph nodes (DLNs). Using a mouse model that allows conditional ablatio...

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!