Oral Fingolimod or Intramuscular Interferon for Relapsing Multiple Sclerosis

A. Cohen, Jeffrey; Barkhof, Frederik; Comı, Gıancarlo; Hartung, Hans‐Peter; Khatri, Bhupendra; Montalbán, Xavier; Pelletier, Jean; Capra, Ruggero; Gallo, Paolo; Izquierdo, Guillermo; Tiel‐Wilck, Klaus; de Vera, Ana; Jin, James; Stites, Tracy; Wu, Stacy; Aradhye, Shreeram; Kappos, Ludwig

doi:10.1056/nejmoa0907839

Public

Oral Fingolimod or Intramuscular Interferon for Relapsing Multiple Sclerosis

Published in New England Journal of Medicine • Jan 20, 2010

Authors:

Jeffrey A. Cohen

Frederik Barkhof

Gıancarlo Comı

Abstract

BACKGROUND: Fingolimod (FTY720), a sphingosine-1-phosphate-receptor modulator that prevents lymphocyte egress from lymph nodes, showed clinical efficacy and improvement on imaging in a phase 2 study involving patients with multiple sclerosis. METHODS: In this 12-month, double-blind, double-dummy stu...

Subject

Fingolimod

Multiple sclerosis

Medicine

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