Ledipasvir and sofosbuvir for previously treated HCV genotype 1 infection.

N, Afdhal; KR, Reddy; DR, Nelson; E, Lawitz; SC, Gordon; E, Schiff; R, Nahass; R, Ghalib; N, Gitlin; R, Herring; J, Lalezari; ZH, Younes; PJ, Pockros; Bisceglie AM, Di; S, Arora; GM, Subramanian; Y, Zhu; H, Dvory-Sobol; JC, Yang; PS, Pang; WT, Symonds; JG, McHutchison; AJ, Muir; M, Sulkowski; P, Kwo

doi:10.1056/nejmoa1316366

Public

Ledipasvir and sofosbuvir for previously treated HCV genotype 1 infection.

Shared by NobleBlocks on Apr 11, 2014 • 12:00 AM UTC

Authors:

Afdhal N

Reddy KR

Nelson DR

Abstract

Background Effective treatment for hepatitis C virus (HCV) genotype 1 infection in patients who have not had a sustained virologic response to prior interferon-based therapy represents an unmet medical need.Methods We conducted a phase 3, randomized, open-label study involving patients infected with...

Discussions