Role of Class A Penicillin-Binding Proteins in PBP5-Mediated β-Lactam Resistance in<i>Enterococcus faecalis</i>

Arbeloa, Ana; Segal, Heidi; Hugonnet, Jean‐Emmanuel; Josseaume, Nathalie; Dubost, Lionnel; Brouard, Jean‐Paul; Gutmann, Laurent; Mengin‐Lecreulx, Dominique; Arthur, Michel

doi:10.1128/jb.186.5.1221-1228.2004

Public

Role of Class A Penicillin-Binding Proteins in PBP5-Mediated β-Lactam Resistance inEnterococcus faecalis

Published in Journal of Bacteriology • Feb 18, 2004

Authors:

Ana Arbeloa

Heidi Segal

Jean‐Emmanuel Hugonnet

Abstract

Peptidoglycan polymerization complexes contain multimodular penicillin-binding proteins (PBP) of classes A and B that associate a conserved C-terminal transpeptidase module to an N-terminal glycosyltransferase or morphogenesis module, respectively. In Enterococcus faecalis, class B PBP5 mediates int...

Subject

Biology

Penicillin binding proteins

Enterococcus faecalis

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