Quantitative Expression of Toll-Like Receptor 1–10 mRNA in Cellular Subsets of Human Peripheral Blood Mononuclear Cells and Sensitivity to CpG Oligodeoxynucleotides

Hornung, Veit; Rothenfußer, Simon; Britsch, Stefanie; Krug, Anne; Jahrsdörfer, Bernd; Giese, Thomas; Endres, Stefan; Hartmann, Gunther

doi:10.4049/jimmunol.168.9.4531

Public

Quantitative Expression of Toll-Like Receptor 1–10 mRNA in Cellular Subsets of Human Peripheral Blood Mononuclear Cells and Sensitivity to CpG Oligodeoxynucleotides

Published in The Journal of Immunology • May 1, 2002

Authors:

Veit Hornung

Simon Rothenfußer

Stefanie Britsch

Abstract

The Toll-like receptor (TLR)9 is critical for the recognition of immunostimulatory CpG motifs but may cooperate with other TLRs. We analyzed TLR1-10 mRNA expression by using quantitative real-time PCR in highly purified subsets of human PBMC and determined the sensitivity of these subsets to CpG oli...

Subject

TLR9

CpG Oligodeoxynucleotide

TLR7

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!