Phenotype variability in progranulin mutation carriers: a clinical, neuropsychological, imaging and genetic study.

Ber I, Le; A, Camuzat; D, Hannequin; F, Pasquier; E, Guedj; A, Rovelet-Lecrux; V, Hahn-Barma; der Zee J, van; F, Clot; S, Bakchine; M, Puel; M, Ghanim; L, Lacomblez; J, Mikol; V, Deramecourt; P, Lejeune; la Sayette V, de; S, Belliard; M, Vercelletto; C, Meyrignac; Broeckhoven C, Van; JC, Lambert; P, Verpillat; D, Campion; MO, Habert; B, Dubois; A, Brice

doi:10.1093/brain/awn012

Public

Phenotype variability in progranulin mutation carriers: a clinical, neuropsychological, imaging and genetic study.

Shared by NobleBlocks on Feb 1, 2008 • 12:00 AM UTC

Authors:

Le Ber I

Camuzat A

Hannequin D

Abstract

Frontotemporal dementia (FTD), characterized by behavioural and language disorders, is a clinically, genetically and pathologically heterogeneous group of diseases. The most recently identified of the four known genes is GRN, associated with 17q-linked FTD with ubiquitin-immunoreactive inclusions. G...

Discussions