High Nasopharyngeal Pneumococcal Density, Increased by Viral Coinfection, Is Associated With Invasive Pneumococcal Pneumonia

Wolter, Nicole; Tempia, Stefano; Cohen, Cheryl; A. Madhi, Shabir; Venter, Marietjie; Moyes, Jocelyn; Walaza, Sibongile; Malope‐Kgokong, Babatyi; J. Groome, Michelle; du Plessis, Mignon; Magomani, Victoria; Pretorius, Marthi; Hellferscee, Orienka; Dawood, Halima; Kahn, Kathleen; Variava, Ebrahim; P. Klugman, Keith; von Gottberg, Anne

doi:10.1093/infdis/jiu326

Public

High Nasopharyngeal Pneumococcal Density, Increased by Viral Coinfection, Is Associated With Invasive Pneumococcal Pneumonia

Published in The Journal of Infectious Diseases • Jun 6, 2014

Authors:

Nicole Wolter

Stefano Tempia

Cheryl Cohen

Abstract

BACKGROUND: We identified factors associated with pneumococcal colonization, high colonization density, and invasive pneumococcal pneumonia among patients hospitalized with acute lower respiratory tract infections (ALRTIs). METHODS: In 2010, 4025 cases were enrolled in surveillance in South Africa. ...

Subject

Coinfection

Pneumonia

Pneumococcal pneumonia

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