Epithelioid Glioblastomas and Anaplastic Epithelioid Pleomorphic Xanthoastrocytomas—Same Entity or First Cousins?

Alexandrescu, Sanda; Korshunov, Andrey; Hui Lai, Siang; Dabiri, Salma; Patil, Sushama; Li, Rong; Shih, Chie‐Schin; M. Bonnin, José; Baker, Jonathan; Du, Emma; Scharnhorst, David; Samuel, David; W. Ellison, David; Perry, Arie

doi:10.1111/bpa.12295

Public

Epithelioid Glioblastomas and Anaplastic Epithelioid Pleomorphic Xanthoastrocytomas—Same Entity or First Cousins?

Published in Brain Pathology • Aug 3, 2015

Authors:

Sanda Alexandrescu

Andrey Korshunov

Siang Hui Lai

Abstract

Epithelioid glioblastoma (eGBM) and pleomorphic xanthoastrocytoma (PXA) with anaplastically transformed foci (ePXA) show overlapping features. Eleven eGBMs and 5 ePXAs were reviewed and studied immunohistochemically. Fluorescence in situ hybridization for EGFR amplification, PTEN deletion and ODZ3 d...

Subject

Pleomorphic xanthoastrocytoma

Pathology

PTEN

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