Microtubule-interfering Agents Activate c-Jun N-terminal Kinase/Stress-activated Protein Kinase through Both Ras and Apoptosis Signal-regulating Kinase Pathways

Wang, Tzu‐Hao; Wang, Hsin-Shih; Ichijo, Hidenori; Giannakakou, Paraskevi; S. Foster, James; Fojo, Tito; Wimalasena, Jay

doi:10.1074/jbc.273.9.4928

Public

Microtubule-interfering Agents Activate c-Jun N-terminal Kinase/Stress-activated Protein Kinase through Both Ras and Apoptosis Signal-regulating Kinase Pathways

Published in Journal of Biological Chemistry • Feb 1, 1998

Authors:

Tzu‐Hao Wang

Hsin-Shih Wang

Hidenori Ichijo

Abstract

The essential cellular functions associated with microtubules have led to a wide use of microtubule-interfering agents in cancer chemotherapy with promising results. Although the most well studied action of microtubule-interfering agents is an arrest of cells at the G2/M phase of the cell cycle, oth...

Subject

Cell biology

Nocodazole

ASK1

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!