Lipopolysaccharide activates an innate immune system response in human adipose tissue in obesity and type 2 diabetes

J. Creely, S.; G. McTernan, P.; M. Kusminski, C.; M. Fisher, ff.; F. Da Silva, N.; Khanolkar, M.; Evans, M.; L. Harte, A.; Kumar, S.

doi:10.1152/ajpendo.00302.2006

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Lipopolysaccharide activates an innate immune system response in human adipose tissue in obesity and type 2 diabetes

Shared by NobleBlocks on Mar 1, 2007 • 12:00 AM UTC

Authors:

S. J. Creely

P. G. McTernan

C. M. Kusminski

Abstract

Type 2 diabetes (T2DM) is associated with chronic low-grade inflammation. Adipose tissue (AT) may represent an important site of inflammation. 3T3-L1 studies have demonstrated that lipopolysaccharide (LPS) activates toll-like receptors (TLRs) to cause inflammation. For this study, we 1) examined act...

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