A Monte Carlo Approach Successfully Identifies Randomness in Multiple Sequence Alignments : A More Objective Means of Data Exclusion

Misof, Bernhard; Misof, Katharina

doi:10.1093/sysbio/syp006

Public

A Monte Carlo Approach Successfully Identifies Randomness in Multiple Sequence Alignments : A More Objective Means of Data Exclusion

Published in Systematic Biology • Feb 1, 2009

Authors:

Bernhard Misof

Katharina Misof

Abstract

Random similarity of sequences or sequence sections can impede phylogenetic analyses or the identification of gene homologies. Additionally, randomly similar sequences or ambiguously aligned sequence sections can negatively interfere with the estimation of substitution model parameters. Phylogenomic...

Subject

Randomness

Similarity (geometry)

Pairwise comparison

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