Breast Cancer Molecular Subtypes Respond Differently to Preoperative Chemotherapy

Rouzier, Roman; M. Perou, Charles; Fraser Symmans, W.; K. Ibrahim, Nuhad; Cristofanilli, Massimo; Anderson, K.; R. Hess, Kenneth; Stec, James; Ayers, Mark; J. Wagner, Peter; Morandi, Paolo; Fan, Chang; Islam, Rabiul; S. Ross, Jeffrey; N. Hortobágyi, Gabriel; Pusztai, Lajos

doi:10.1158/1078-0432.ccr-04-2421

Public

Breast Cancer Molecular Subtypes Respond Differently to Preoperative Chemotherapy

Published in Clinical Cancer Research • Aug 15, 2005

Authors:

Roman Rouzier

Charles M. Perou

W. Fraser Symmans

Abstract

PURPOSE: Molecular classification of breast cancer has been proposed based on gene expression profiles of human tumors. Luminal, basal-like, normal-like, and erbB2+ subgroups were identified and were shown to have different prognoses. The goal of this research was to determine if these different mol...

Subject

Breast cancer

Chemotherapy

Oncology

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