Liver Histology and Surgical Outcomes After Preoperative Chemotherapy With Fluorouracil Plus Oxaliplatin in Colorectal Cancer Liver Metastases

A. Aloia, Thomas; Sebagh, Mylène; Plasse, M.; Karam, Vincent; Lévi, Françis; Giacchetti, Sylvie; Azoulay, Daniel; Bismuth, Henri; Castaing, Denis; Adam, René

doi:10.1200/jco.2006.05.8156

Public

Liver Histology and Surgical Outcomes After Preoperative Chemotherapy With Fluorouracil Plus Oxaliplatin in Colorectal Cancer Liver Metastases

Published in Journal of Clinical Oncology • Oct 30, 2006

Authors:

Thomas A. Aloia

Mylène Sebagh

M. Plasse

Abstract

PURPOSE: Preoperative chemotherapy for colorectal liver metastases (CLM) can produce histologic changes in the nontumor-bearing liver (NTBL) that may impact on surgical outcomes. PATIENTS AND METHODS: From a cohort of 303 patients treated for CLM with liver resection, 92 patients (75 received preope...

Subject

Medicine

Oxaliplatin

Chemotherapy

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