Early adversity and 5-HTT/BDNF genes: new evidence of gene–environment interactions on depressive symptoms in a general population

Aguilera, Mari; Arias, Bárbara; Wichers, Marieke; Barrantes‐Vidal, Neus; Moya, Jorge; Villa, Helena; van Os, Jim; I. Ibáñez, Manuel; A. Ruipérez, Marı́a; Ortet, Generós; Fañanás, Lourdes

doi:10.1017/s0033291709005248

Public

Early adversity and 5-HTT/BDNF genes: new evidence of gene–environment interactions on depressive symptoms in a general population

Published in Psychological Medicine • Feb 12, 2009

Authors:

Mari Aguilera

Bárbara Arias

Marieke Wichers

Abstract

BACKGROUND: Adverse childhood experiences have been described as one of the major environmental risk factors for depressive disorder. Similarly, the deleterious impact of early traumatic experiences on depression seems to be moderated by individual genetic variability. Serotonin transporter (5-HTT) ...

Subject

Serotonin transporter

CTQ tree

5-HTTLPR

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