Interleukin 13 and Interleukin 4 Receptor-α Polymorphisms in Rhinitis and Asthma

W. B. Bottema, R.; M. Nolte, Ilja; D. Howard, Timothy; H. Koppelman, Gerard; E. J. Dubois, A.; de Meer, Gea; Kerkhof, Marjan; R. Bleecker, Eugene; A. Meyers, Deborah; S. Postma, Dirkje

doi:10.1159/000314366

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Interleukin 13 and Interleukin 4 Receptor-α Polymorphisms in Rhinitis and Asthma

Published in International Archives of Allergy and Immunology • Jan 1, 2010

Authors:

R. W. B. Bottema

Ilja M. Nolte

Timothy D. Howard

Abstract

BACKGROUND: Asthma and rhinitis may represent two manifestations of the same airway disease. Genetic research can increase our understanding of their common or distinct pathogenesis. IL13 and IL4R polymorphisms are associated with asthma and show gene-gene interaction in asthma. Their role in rhinit...

Subject

Asthma

Immunology

Proband

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