Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study

Kumarasamy, Kanimozhi; A. Toleman, Mark; R. Walsh, Timothy; Bagaria, Jay; Butt, Fafhana; Balakrishnan, Ravi; Chaudhary, Uma; Doumith, Michel; G. Giske, Christian; Irfan, Seema; Krishnan, Padma; Kumar, Anil; Maharjan, Sunil; Mushtaq, Shazad; Noorie, Tabassum; L. Paterson, David; Pearson, A.; Perry, Claire; Pike, Rachel; Rao, Bhargavi; Ray, Ujjwayini; Sarma, Jayanta; Sharma, Madhu; Sheridan, Elizabeth; A. Thirunarayan, M.; F. Turton, Jane; Upadhyay, Supriya; Warner, Marina; Welfare, William; M. Livermore, David; Woodford, Neil

doi:10.1016/s1473-3099(10)70143-2

Public

Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study

Published in The Lancet Infectious Diseases • Aug 11, 2010

Authors:

Kanimozhi Kumarasamy

Mark A. Toleman

Timothy R. Walsh

Abstract

BACKGROUND: Gram-negative Enterobacteriaceae with resistance to carbapenem conferred by New Delhi metallo-beta-lactamase 1 (NDM-1) are potentially a major global health problem. We investigated the prevalence of NDM-1, in multidrug-resistant Enterobacteriaceae in India, Pakistan, and the UK. METHODS...

Subject

Tigecycline

Colistin

Klebsiella pneumoniae

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