Anatomical correlates of the distribution of the pathological changes in the neocortex in Alzheimer disease.

Pearson, R.C.A.; M. Esiri, Margaret; W. Hiorns, R.; K Wilcock, G; Powell, T.P.S.

doi:10.1073/pnas.82.13.4531

Public

Anatomical correlates of the distribution of the pathological changes in the neocortex in Alzheimer disease.

Published in Proceedings of the National Academy of Sciences • Jul 1, 1985

Authors:

R.C.A. Pearson

Margaret M. Esiri

R. W. Hiorns

Abstract

The numbers and distribution of the neurofibrillary tangles and neuritic plaques have been determined in several areas of the neocortex in brains affected by various degrees of severity of Alzheimer disease. The homotypical cortex of the "association" areas of the temporal, parietal, and frontal lob...

Subject

Neocortex

Senile plaques

Neuroscience

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