Identification and characterization of a functional, alternatively spliced Toll‐like receptor 7 (TLR7) and genomic disruption of TLR8 in chickens

J. Philbin, Victoria; Iqbal, Muhammad; Boyd, Yvonne; Goodchild, Marianne; K. Beal, Richard; Bumstead, Nat; R. Young, John; L. Smith, Adrian

doi:10.1111/j.1365-2567.2005.02125.x

Public

Identification and characterization of a functional, alternatively spliced Toll‐like receptor 7 (TLR7) and genomic disruption of TLR8 in chickens

Published in Immunology • Mar 21, 2005

Authors:

Victoria J. Philbin

Muhammad Iqbal

Yvonne Boyd

Abstract

Based upon the recognition of antiviral compounds and single stranded viral RNA the Toll-like receptors TLR7 and TLR8 are suggested to play a significant role in initiating antiviral immune responses. Here we report the molecular characterization of the chicken TLR7/8 loci which revealed an intact T...

Subject

TLR7

Biology

Molecular biology

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