Quinoline Derivatives as Promising Inhibitors of Antibiotic Efflux Pump in Multidrug Resistant Enterobacter Aerogenes Isolates

Mahamoud, Abdallah; Chevalier, Jacqueline; Davin‐Regli, Anne; Barbe, Jacques; Pagès, Jean‐Marie

doi:10.2174/138945006777709557

Public

Quinoline Derivatives as Promising Inhibitors of Antibiotic Efflux Pump in Multidrug Resistant Enterobacter Aerogenes Isolates

Published in Current Drug Targets • Jun 28, 2006

Authors:

Abdallah Mahamoud

Jacqueline Chevalier

Anne Davin‐Regli

Abstract

Efflux pumps protect the bacterial cell by expelling toxic compounds before they reach intracellular targets. Because this mechanism actively contributes to the resistance of a given bacterium to more than one class of antibiotics, molecules that are able to block the relevant efflux pump are of pot...

Subject

Efflux

Enterobacter aerogenes

Antibiotics

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