Feasibility of a High-Flux Anticancer Drug Screen Using a Diverse Panel of Cultured Human Tumor Cell Lines

Monks, Anne; A. Scudiero, Dominic; Skehan, Philip; H. Shoemaker, Robert; D. Paull, Kenneth; T. Vistica, David; Hose, Curtis; W. Langley, James; Cronise, P.; Vaigro-Wolff, Anne; Gray-Goodrich, M.; Campbell, H.; Mayo, J.; Boyd, Marie

doi:10.1093/jnci/83.11.757

Public

Feasibility of a High-Flux Anticancer Drug Screen Using a Diverse Panel of Cultured Human Tumor Cell Lines

Published in JNCI Journal of the National Cancer Institute • Jun 5, 1991

Authors:

Anne Monks

Dominic A. Scudiero

Philip Skehan

Abstract

We describe here the development and implementation of a pilot-scale, in vitro, anticancer drug screen utilizing a panel of 60 human tumor cell lines organized into subpanels representing leukemia, melanoma, and cancers of the lung, colon, kidney, ovary, and central nervous system. The ultimate goal...

Subject

Sulforhodamine B

Cell culture

Viability assay

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