Loss of miR-133a expression associated with poor survival of breast cancer and restoration of miR-133a expression inhibited breast cancer cell growth and invasion

Wu, Zhengsheng; Wang, Chao-Qun; Xiang, Ru; Liu, Xue; Ye, Shan; Yang, Xue-qing; Zhang, Gui-Hong; Xu, Xiao-Chun; Zhu, Tao; Wu, Qiang

doi:10.1186/1471-2407-12-51

Public

Loss of miR-133a expression associated with poor survival of breast cancer and restoration of miR-133a expression inhibited breast cancer cell growth and invasion

Published in BMC Cancer • Feb 1, 2012

Authors:

Zhengsheng Wu

Chao-Qun Wang

Ru Xiang

Abstract

BACKGROUND: miRNAs, endogenous oligonucleotide RNAs, play an important role in mammary gland carcinogenesis and tumor progression. Detection of their expression and investigation of their functions could lead to discovery of novel biomarkers for breast cancer. METHODS: In situ hybridization was used...

Subject

Breast cancer

Gene knockdown

Carcinogenesis

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