Nevirapine and efavirenz elicit different changes in lipid profiles in antiretroviral-therapy-naive patients infected with HIV-1.

van Leth, Frank; Phanuphak, Prahpan; Stroes, Erik; Gazzard, Brian; Cahn, Pedro; Raffi, François; Wood, Robin; Bloch, Mark; Katlama, Christine; J P Kastelein, John; Schechter, Mauro; L Murphy, Robert; Horban, Andrzej; B Hall, David; M A Lange, Joep; Reiss, Peter

doi:10.1371/journal.pmed.0010019

Public

Nevirapine and efavirenz elicit different changes in lipid profiles in antiretroviral-therapy-naive patients infected with HIV-1.

Published in PLoS medicine • Oct 1, 2004

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Authors:

Frank van Leth

,

Prahpan Phanuphak

,

Erik Stroes

Abstract

BACKGROUND: Patients infected with HIV-1 initiating antiretroviral therapy (ART) containing a non-nucleoside reverse transcriptase inhibitor (NNRTI) show presumably fewer atherogenic lipid changes than those initiating most ARTs containing a protease inhibitor. We analysed whether lipid changes diff...

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