Mapping the Interactions between the NS4B and NS3 Proteins of Dengue Virus

Zou, Jing; Tian Lee, Le; Yin Wang, Qing; Xie, Xuping; Lu, Siyan; Hoe Yau, Yin; Yuan, Zhiming; Geifman Shochat, Susana; Kang, CongBao; Lescar, Julien; Shi, Pei‐Yong

doi:10.1128/jvi.03454-14

Public

Mapping the Interactions between the NS4B and NS3 Proteins of Dengue Virus

Published in Journal of Virology • Jan 15, 2015

Authors:

Jing Zou

Le Tian Lee

Qing Yin Wang

Abstract

UNLABELLED: Flavivirus RNA synthesis is mediated by a multiprotein complex associated with the endoplasmic reticulum membrane, named the replication complex (RC). Within the flavivirus RC, NS4B, an integral membrane protein with a role in virulence and regulation of the innate immune response, binds...

Subject

NS3

Biology

Dengue virus

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