Bevacizumab plus Radiotherapy–Temozolomide for Newly Diagnosed Glioblastoma

Chinot, Olivier; Wick, Wolfgang; Mason, Warren; Henriksson, Roger; Saran, Frank; Nishikawa, Ryo; Carpentier, Alain; Hoang‐Xuan, Khê; Kavan, Petr; Cernea, Dana; A. Brandes, Alba; Hilton, Magalie; E. Abrey, Lauren; F. Cloughesy, Timothy

doi:10.1056/nejmoa1308345

Public

Bevacizumab plus Radiotherapy–Temozolomide for Newly Diagnosed Glioblastoma

Published in New England Journal of Medicine • Feb 19, 2014

Authors:

Olivier Chinot

Wolfgang Wick

Warren Mason

Abstract

BACKGROUND: Standard therapy for newly diagnosed glioblastoma is radiotherapy plus temozolomide. In this phase 3 study, we evaluated the effect of the addition of bevacizumab to radiotherapy-temozolomide for the treatment of newly diagnosed glioblastoma. METHODS: We randomly assigned patients with s...

Subject

Medicine

Temozolomide

Bevacizumab

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