Plasma Cathepsin D Levels: A Novel Tool to Predict Pediatric Hepatic Inflammation

M. A. Walenbergh, Sofie; Houben, Tom; Hendrikx, Tim; L. J. Jeurissen, Mike; J. van Gorp, Patrick; Vreugdenhil, Anita; Adriaanse, Marlou; A. Buurman, Wim; H. Hofker, Marten; Mosca, Antonella; Lindsey, Patrick; Alisi, Anna; Liccardo, Daniela; Panera, Nadia; H. Koek, Ger; Nobili, Valério; Shiri‐Sverdlov, Ronit

doi:10.1038/ajg.2015.29

Public

Plasma Cathepsin D Levels: A Novel Tool to Predict Pediatric Hepatic Inflammation

Published in The American Journal of Gastroenterology • Mar 1, 2015

Authors:

Sofie M. A. Walenbergh

Tom Houben

Tim Hendrikx

Abstract

OBJECTIVES: Nonalcoholic steatohepatitis (NASH) is the most severe form of a hepatic condition known as nonalcoholic fatty liver disease (NAFLD). NASH is histologically characterized by hepatic fat accumulation, inflammation, and ballooning, and eventually coupled with fibrosis that, in turn, may pr...

Subject

Inflammation

Medicine

Internal medicine

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