A novel method for efficient amplification of whole hepatitis B virus genomes permits rapid functional analysis and reveals deletion mutants in immunosuppressed patients

Günther, Stephan; Li, Bichun; Miska, Stefan; H. Krüger, Detlev; Meisel, H; Will, Hans

doi:10.1128/jvi.69.9.5437-5444.1995

Public

A novel method for efficient amplification of whole hepatitis B virus genomes permits rapid functional analysis and reveals deletion mutants in immunosuppressed patients

Published in Journal of Virology • Sep 1, 1995

Authors:

Stephan Günther

Bichun Li

Stefan Miska

Abstract

Current knowledge of hepatitis B virus (HBV) sequence heterogeneity is based mainly on sequencing of amplified subgenomic HBV fragments. Here, we describe a method which allows sensitive amplification and simplified functional analysis of full-length HBV genomes with or without prior cloning. By thi...

Subject

Biology

Subgenomic mRNA

Hepatitis B virus

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!